A train derailed in East Palestine, Ohio on Friday night causing a massive fire in the area, local media reported.
Emergency crews have been evacuating residents from their homes within a one-mile radius of the fire, according to several reports.
It was not immediately clear if there were any casualties. The East Palestine police department did not immediately respond to a Reuters request for details.
Freight railroad company Norfolk Southern Corp is "coordinating closely with local first responders while mobilizing our own teams", a company spokesperson said in an emailed statement.
The person did not immediately respond to queries about what the train was carrying or what caused the derailment.