At least 20 people died in a fire at the Mahdia Secondary School in Guyana, AFP news agency reported on Monday citing a government official.
"Five planes have already taken off to Mahdia to support the regional health officials with additional medical supplies and medivacs," the government said in a statement.
Seven children were prepared to be sent by medivac to Georgetown, it said.
The prime minister is leading a team of cabinet and other officials to Madhia while Minister of Home Affairs Minister Robeson Benn is already on the ground.