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15 pandemic diseases that changed history

Humanity has faced many calamities and diseases throughout history. Over 2500 years, millions of lives have been lost due to pandemic diseases. These diseases not only changed history but also impacted fundamental areas such as the economy, health, and social thought. Pandemics have been historical factors that have wounded societies and led to significant population losses.

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1889 - Russian Flu: The Russian Flu, the first widespread influenza pandemic in history, began in 1889 in the Russian Empire, centered around Siberia and Kazakhstan. The Russian Flu, spreading from Finland to Europe, reached America a year later. By 1890, the Russian Flu had caused the deaths of nearly 400,000 people worldwide.