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15 pandemic diseases that changed history

Humanity has faced many calamities and diseases throughout history. Over 2500 years, millions of lives have been lost due to pandemic diseases. These diseases not only changed history but also impacted fundamental areas such as the economy, health, and social thought. Pandemics have been historical factors that have wounded societies and led to significant population losses.

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The Spanish flu, which quickly spread across the entire world, actually originated not in Spain but in the state of New Mexico in the U.S. During World War I, the virus carried by US soldiers deployed to fight in Europe led to the deaths of 50-100 million people within 18 months. This accounted for approximately 15% of the world's population at the time.