"Within the framework of TUR-RF Agreement/Protocol, the 16th TUR-RF Combined Land Patrol on M-4 Highway in Idlib was conducted with the participation of land and air elements," the ministry said in an official statement.
The M4 highway, also known as the Aleppo-Al Hasakah road, is about 30 kilometers (19 miles) from Turkey's southern border.
This March, Ankara and Moscow agreed on a protocol urging parties to "cease all military actions along the line of contact in the Idlib de-escalation area."
The protocol said joint Turkish-Russian patrols would begin on March 15 along the M4 highway from the settlement of Trumba-2 km (1.2 mi) west of Saraqib-to the settlement of Ain al-Havr.
Idlib has long been under siege by Assad regime forces and its allies, and previous cease-fires for the region were plagued by violations.
Turkey has worked to protect the local civilian population as well as rid the wider region of terrorist elements.