Israeli strike hits Damascus residential building: state media

An Israeli strike on Damascus killed five people in a building where "Iran-aligned leaders" were meeting on Saturday, a war monitor said, as regional tensions soar over the Israel-Hamas war.

"An Israeli missile strike targeted a four-storey building, killing five people... and destroying the whole building where Iran-aligned leaders were meeting," said the Syrian Observatory for Human Rights.

The British-based monitor with a network of sources inside Syria said the targeted neighbourhood is known to be a high-security zone home to leaders of Iran's Islamic Revolutionary Guard Corps (IRGC) and pro-Iran Palestinian factions.

"They were for sure targeting senior members" of those groups, said Observatory director Rami Abdel Rahman.

The mid-morning strike, which caused a large plume of smoke to billow into the sky, was also reported by Syrian state media.

"An attack targeted a residential building in the Mazzeh neighbourhood in Damascus, resulting from an Israeli aggression," the official SANA news agency reported. It did not say if there were any casualties.

The Mazzeh area is home to the United Nations' headquarters, embassies and restaurants.

"I heard the explosion clearly in the western Mazzeh area, and I saw a large cloud of smoke," a resident told AFP.

"The sound was similar to a missile explosion, and minutes later I heard the sound of ambulances," he added.