Israel attacked a shelter belonging to medical charity Doctors Without Borders (MSF) in the Gaza Strip on Tuesday, killing at least two people.
"Tonight Israeli forces conducted an operation in Al Mawasi, Khan Younis, Gaza, where a shelter hosting MSF staff and their families was shelled," MSF said on X.
"While details are still emerging, ambulance crews have now reached the site, where at least two family members of our colleagues have been killed and six people wounded. We are horrified by what has taken place," it added.
Israel has pounded the Gaza Strip since a cross-border attack by the Palestinian group Hamas in October, in which nearly 1,200 Israelis are believed to have been killed.
The death toll from Israel's offensive on the Gaza Strip has jumped to 29,195, the Palestinian Health Ministry said Tuesday.
Another 69,170 people have been injured so far.
About 85% of Gazans have been displaced by the Israeli onslaught, while all of them are food insecure, according to the UN. Hundreds of thousands of people are living without shelter, and less than half of the aid trucks are entering the territory than before the start of the conflict.
Israel stands accused of genocide at the International Court of Justice. An interim ruling in January ordered Tel Aviv to stop genocidal acts and take measures to guarantee that humanitarian assistance is provided to civilians in Gaza.