A U.S. base in western Syria's Homs province came under a drone attack, according to local sources on Sunday.
The suicide drone was shot down by U.S. soldiers at the base in al-Tanf area near the border with Jordan late Saturday, the sources said.
No injuries were reported.
The U.S. base came under a similar drone attack last April 7.
Groups backed by Iran occasionally target American bases on the eastern bank of the Euphrates River using missiles and suicide drones.