Juventus' 1-0 derby win over Torino came at a cost with prized striker Gonzalo Higuain limping off with an apparent left ankle injury Sunday.
Higuain's status will be a big concern for Juventus' pursuit of a seventh straight Serie A title as well as the return leg of the Champions League last 16 against Tottenham.
Higuain was left grimacing on the pitch three minutes in after making contact near the endline with Torino goalkeeper Salvatore Sirigu, who broke up a Juventus chance.
After staying on for another 10 minutes, Higuain exited and was replaced by Federico Bernardeschi.
Less than 20 minutes later, Bernardeschi set up Alex Sandro's goal, dribbling past a defender then providing the cross for Sandro to tap in from close range.
It was Juventus' ninth straight win and it moved the Bianconeri two points ahead of Napoli at the top of the standings.
Napoli was hosting relegation-threatened Spal later.
Higuain scored twice when Juventus drew 2-2 with Tottenham on Tuesday. The return leg is scheduled for London on March 7.