Galatasaray drew 1-1 with Russian side Lokomotiv Moscow at home on Thursday.
Sofiane Feghouli gave the Lions a 1-0 lead in the 43rd minute at Nef Stadium in Istanbul but Francois Kamano scored the equalizer in the 72nd minute.
The Turkish club still remain atop of Group E with eight points.
Lokomotiv Moscow have two points to sit at the bottom of the group.