The state, the country's fourth most populous, had restricted eligibility to residents who are at least 60 years old, have pre-existing health conditions or are essential workers, especially those who come in contact with the public.
"We are dropping the age and vaccinating more people," Cuomo said at a church in Mount Vernon, New York, where he launched a campaign to encourage houses of worship to make themselves available as vaccination sites.
With the change, which takes effect on Tuesday, New York joins Florida, the third largest state, which lowered its eligibility age on Monday, and a handful of other states that have made vaccines available to healthy people who are 50 years old or younger.
Alaska has the lowest eligibility age at 16. Its vaccination rate is among the highest in the country, with 31.5% of its residents having received at least one dose, according to data from the Centers for Disease Control and Prevention (CDC).
New York has administered at least one dose to 26.1% of its residents and Florida has administered it to 23.8%, according to the CDC, which updated its data on Sunday.
Nationwide, the CDC said 24.9% of U.S. residents have received at least one dose of a vaccine, and 13.5% are fully vaccinated.
