Fighting is raging on multiple fronts in Ukraine, with intense combat underway in the besieged port city of Mariupol — the site of some of the war's greatest suffering. Ukrainian officials say their forces there are battling the Russians over the Azovstal steel plant, one of the biggest in Europe.
Overnight, Ukrainian President Volodymyr Zelensky accused the Kremlin of deliberately creating "a humanitarian catastrophe," but also appealed for Russian President Vladimir Putin to meet him for direct talks.
The U.N. migration agency says nearly 6.5 million people have been displaced inside Ukraine, along with the 3.2 million refugees who have already fled the country. Ukraine says thousands have been killed.
Here are some key things to know about the conflict:
The Ukrainians announced Saturday that 10 humanitarian corridors have been agreed on with the Russians — one from Mariupol, several in the region of the capital, Kyiv, and in the Luhansk region. Humanitarian aid deliveries are also planned for the city of Kherson, currently under Russian control.
In Mariupol, Ukrainian troops were losing control of the key Azovstal steel plant, now damaged and heavily contested, according to an adviser to Ukraine's interior minister.
"We have lost this economic giant. In fact, one of the largest metallurgical plants in Europe is actually being destroyed," Vadym Denysenko said in televised remarks.
Zelensky said in his Friday nighttime video address to the nation that more than 9,000 people were able to leave Mariupol in the past day, and in all more than 180,000 people have been able to flee through humanitarian corridors.
A 38-hour curfew was announced in the southeastern city of Zaporizhzhia, to last from 4 p.m. on Saturday until 6 a.m. Monday. Officials said two missile strikes on the city's suburbs a day earlier killed nine people. Local authorities there say they continue to evacuate people from areas occupied by Russian troops.
The Russian military reported Saturday that it has used its latest hypersonic missile for the first time in combat. A spokesman for the Russian Defense Ministry, Maj. Gen. Igor Konashenkov, said Kinzhal missiles destroyed an underground warehouse storing Ukrainian missiles and aviation ammunition in the western Ivano-Frankivsk region of Ukraine.
Three Russian cosmonauts arrived Friday at the International Space Station, and as they floated into it in zero gravity, they were wearing bright yellow flight suits with blue accents. Those are the colors of the Ukrainian flag.
Later, the cosmonauts were able to talk to family back on Earth, and cosmonaut Oleg Artemyev was asked about the flight suits. He said every crew chooses its own flight suits and "in fact, we had accumulated a lot of yellow material so we needed to use it. So that's why we had to wear yellow."
Since the war started, many people have used the Ukrainian flag and its colors to show solidarity with the country. It was unclear what message, if any, the yellow uniforms were intended to send.
President Joe Biden and China's Xi Jinping spoke Friday for nearly two hours via video as the U.S. looks to deter Beijing from providing military or economic aid for Russia's invasion. Biden described the consequences the Chinese would face from the U.S. if they provide military or economic assistance for Russia's invasion of Ukraine. For his part, Xi urged the U.S. and Russia to negotiate and blamed the U.S. for the crisis.
On Saturday, China's vice foreign minister reiterated blame against NATO for the war, and criticized sanctions against Russia. Le Yucheng said NATO was a "Cold War vestige" and that its expansion could result in "repercussions too dreadful to contemplate" from a major power like Russia.
French President Emmanuel Macron pressed for an immediate cease-fire in a phone call Friday with Putin. German Chancellor Olaf Scholz also pressed Putin for a cease-fire in a Friday conversation.
Biden plans to travel to Europe next week for talks with European leaders about the Russian invasion, and will attend an extraordinary NATO summit in Brussels.
The head of the Russian delegation in talks with Ukrainian officials says the parties have come closer to an agreement on a neutral status for Ukraine — one of the key Russian demands as its offensive continues. Vladimir Medinsky said Friday that the sides also have narrowed their differences on the issue of Ukraine dropping its bid to join NATO.
But Mikhailo Podolyak, an adviser to Zelensky, tweeted: "Our positions are unchanged. Ceasefire, withdrawal of troops & strong security guarantees with concrete formulas."
Britain's foreign secretary meanwhile accused Putin of using the talks as a "smokescreen" while he ramps up violence against the country. Liz Truss told the Times of London newspaper that she was "very skeptical" about Russia's seriousness in the talks, accusing Russian forces of trying to create space to regroup and unblock their stalled campaign.
The U.N. human rights office says that it has recorded a total of 816 civilians killed and 1,333 injured since the Russian invasion began on Feb. 24, though it believes the figures vastly understate the actual toll.
The office of the country's Prosecutor General reported Saturday that a total of 112 children have been killed since the start of the fighting. More than 140 children have been wounded.
Dozens of civilians were killed and injured as a result of attacks over the past 24 hours in the eastern Donetsk region, Ukrainian police said Saturday. At least 37 residential buildings and infrastructure facilities were damaged in the attacks, on eight cities and villages using aviation, rocket and heavy artillery.
Since the start of Russia's invasion of Ukraine, AP journalists are relaying images of destruction, distress, and defiance from across the country.
From Mariupol, police officer Michail Vershnin pleaded from a rubble-strewn street in a video addressed to Western leaders. "Children, elderly people are dying. The city is destroyed and it is wiped off the face of the earth," he said.
A soldier standing guard near the site of the strike in Lviv said he heard three blasts in quick succession around 6 a.m. A nearby resident described his building vibrating from the explosions and people panicking. Smoke continued to rise from the site hours later.
The United States and its allies have put a slew of sanctions in place aimed at crippling the Russian economy. Hundreds of international companies have announced that they are curtailing operations in Russia, and those who remain are under pressure to pull out.
Pope Francis on Friday denounced what he called the "perverse abuse of power" in Russia's war in Ukraine and called for aid for Ukrainians whose identity, history and tradition are under attack. Francis' comments were some of his strongest yet in asserting Ukraine's right to exist as a sovereign state.
Aid agencies are ramping up their efforts to deliver relief supplies to civilians affected by the fighting and refugees who have fled Ukraine. The Polish city of Rzeszow, about 60 miles (100 kilometers) from the Ukrainian border, has become a humanitarian hub for the region.
