President Ebrahim Raisi on Sunday blamed his U.S. counterpart for inciting "chaos, terror, and destruction" in Iran, the official IRNA news agency reported, amid protests that have rocked the country for the past four weeks.
"The American president, who allows himself through his comments to incite chaos, terror and destruction in another country, should be reminded of the eternal words of the founder of the Islamic Republic, who called America the great satan," Raisi said.
"The enemy's plot must be countered by effective measures to resolve people's problems," Raisi added, according to a presidency statement.
Iran has been rocked by protests since 22-year-old Amini's death on September 16, three days after she was arrested by morality police in Tehran for allegedly violating the country's strict dress code for women.
The street violence has led to dozens of deaths, mostly among protesters but also among the security forces, and hundreds have of demonstrators been arrested.
Biden had said Friday that "we stand with the citizens, the brave women of Iran.
"It stunned me what it awakened in Iran. It awakened something that I don't think will be quieted for a long, long time," said the US president.
Earlier Sunday, Iran's foreign affairs spokesman Nasser Kanani had shrugged off Biden's comments, saying that "Iran is too strong for its will to be swayed by the interference... by a politician tired of years of failure."
"We will together defend the independence of Iran," Kanani wrote on Instagram.
On October 6, the United States slapped sanctions on seven senior Iranian officials for involvement in the crackdown.
The US Treasury last month also placed sanctions on the morality police.
