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15 pandemic diseases that changed history

Humanity has faced many calamities and diseases throughout history. Over 2500 years, millions of lives have been lost due to pandemic diseases. These diseases not only changed history but also impacted fundamental areas such as the economy, health, and social thought. Pandemics have been historical factors that have wounded societies and led to significant population losses.

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Leprosy had turned into an epidemic during the Middle Ages. Despite all attempts, the disease's persistence led people to believe it was a divine punishment. At one point, leprosy patients were portrayed as witches and banished outside the cities. Those within the community had to shake a bell to announce their approach.