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15 pandemic diseases that changed history

Humanity has faced many calamities and diseases throughout history. Over 2500 years, millions of lives have been lost due to pandemic diseases. These diseases not only changed history but also impacted fundamental areas such as the economy, health, and social thought. Pandemics have been historical factors that have wounded societies and led to significant population losses.

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1492 Columbus Plague: Christopher Columbus led the Spanish expedition that introduced measles, smallpox, and chickenpox to the Native Americans, thus triggering a major epidemic across the continent. Consequently, up to ninety percent of the existing native population of the Americas perished. For instance, the population of the Taino people, whom Columbus had encountered earlier, plummeted from 60,000 to 500 within a short period.