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15 pandemic diseases that changed history

Humanity has faced many calamities and diseases throughout history. Over 2500 years, millions of lives have been lost due to pandemic diseases. These diseases not only changed history but also impacted fundamental areas such as the economy, health, and social thought. Pandemics have been historical factors that have wounded societies and led to significant population losses.

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Antonine Plague of 165: The plague transmitted by the Huns to the Germans, and then by the Germans to the Romans, spread throughout the entire Roman Empire by Roman soldiers, and from there to the entire continent of Europe. The pandemic lasted for a full 15 years. The plague, which also caused the death of Emperor Marcus Aurelius, exhibited symptoms such as high fever, sore throat, and inflamed wounds.